One Health (OH) has gained considerable prominence since the beginning of the 21st century, among others, driven by the recent epidemics and the  increasing importance of zoonotic diseases. Yet, despite the holistic  and multidimensional nature of OH, to date, most emphasis has been on  the interactions between animal and human health, with considerably less  attention to environmental and plant health. However, there is growing  evidence that the challenges of climate change, growing food and  nutritional insecurity, and biodiversity loss can best be addressed  within the context of the OH framework. Conceptionally, Integrated Pest  Management (IPM) could perfectly fit into such an approach, but  historically, IPM has been practiced very much in a compartmentalized  manner. New approaches such as Regenerative Agriculture and Sustainable  Intensification offer solutions to how to successfully embed IPM into a  OH framework.